Metabolism Diazepam is N-demethylated by CYP3A4 and 2C19 into the Lively metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 for the Energetic metabolite temazepam.Keep track of neonates subjected to diazepam through pregnancy or labor for signs of sedation and check neonates subjected to diazepam through pregnancy for indications of with